HLA Typing & Immune Compatibility
Full human leukocyte antigen profile
High-resolution HLA typing across Class I (A, B, C) and Class II (DR, DQ, DP) loci — essential for transplant compatibility, autoimmune disease risk, pharmacogenomic HLA-drug reactions, and ancestry.
Istanbul, Turkey
€350
Results in 12 days
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Postal saliva kit — no clinic visit required
Collect from home, post back in the pre-paid envelope. Results delivered digitally in 12 days.
What your saliva
sample reveals
HLA-A, B, C (Class I — 4-digit resolution)
HLA-DR, DQ, DP (Class II — 4-digit resolution)
Pharmacogenomic HLA alerts (abacavir, carbamazepine, allopurinol)
HLA-B27 (ankylosing spondylitis risk)
Immunology compatibility report
Best for: Anyone requiring transplant matching, with unexplained inflammatory arthritis, or on HLA-risk medications
Explore each panel
Browse every category covered in your HLA Typing & Immune Compatibility — click a marker to see the action it unlocks.
Your Human Leukocyte Antigen profile — the master controller of your immune system's self/non-self recognition.
HLA-DRB1 (RA)
HLA-DRB1 (chr6)
HLA-DQ2 (T1D/Coeliac)
HLA-DQA1/DQB1 (chr6)
HLA-DR2 (MS)
HLA-DRB1*15:01 (chr6)
HLA-B27 (SpA)
HLA-B27 (chr6)
Turn data into action
Every finding in your report comes with a concrete next step. Here's what your results can unlock.
Start Proactive Autoimmune Monitoring
Before onsetTriggered by: HLA-DRB1, PTPN22, or other autoimmune variants
10 yrs
earlier detection vs. symptom-based diagnosis
Click to collapse
What this result reveals:
Whether you carry the specific HLA haplotypes and non-HLA variants that significantly increase risk of RA, lupus, MS, or type 1 diabetes — and the biomarkers to monitor annually that detect autoimmunity 5–10 years before clinical symptoms.
Begin annual monitoring: ANA, anti-CCP, anti-dsDNA, and thyroid antibodies — a panel your GP can order as a single request
Implement autoimmune-protective lifestyle: Mediterranean diet, vitamin D optimisation, gut microbiome support
Share your HLA result with first-degree relatives — many HLA haplotypes are inherited in clusters
Early detection of pre-clinical autoimmunity (positive antibodies before symptoms) gives a 5–10 year window to intervene with lifestyle and monitoring before organ damage occurs.
Lower Your Inflammatory Setpoint
ModifiableTriggered by: IL-6 high producer or PTPN22 risk variant
−45%
serum IL-6 reduction achievable
Click to see the full action protocol →
HLA-B27 — Interpret Your Back Pain Correctly
Diagnostic powerTriggered by: HLA-B27 positive result
20–100×
elevated SpA risk in HLA-B27 positive patients
Click to see the full action protocol →
Every action protocol above is included in your digital report, reviewed by a specialist.
Who benefits most
Family history of autoimmune disease
A parent or sibling with rheumatoid arthritis, lupus, or MS. Knowing your HLA haplotype allows early monitoring and targeted lifestyle intervention — before onset.
Persistent inflammation
High-sensitivity CRP, chronic joint pain, or a body that takes far too long to recover. Your cytokine gene variants determine your inflammatory setpoint.
Chronic fatigue or frequent infections
Post-viral fatigue, long COVID symptoms, or an immune system that simply never quite recovers. Immune genetics reveal whether there's a structural genetic explanation.
60 pages of actionable insight
Not a raw data dump — a structured clinical report written in plain language, reviewed by your specialist before delivery, with every finding mapped to a concrete action.
HLA Typing & Immune Compatibility — Genetic Report
Sample results · For illustrative purposes
Positive
HLA-B27 status
SpA monitoring needed
High
IL-6 level
Inflammatory setpoint
Moderate
Autoimmune risk
PTPN22 variant
Deficient
Skin barrier
FLG null — eczema risk
HLA-DRB1 (RA)
HLA Typing
HLA-DQ2 (Coeliac)
HLA Typing
HLA-DR2 (MS)
HLA Typing
HLA-B27 (SpA)
HLA Typing
+ 6 more markers in your full report
Report delivered digitally in 12 days from sample receipt. Reviewed by a specialist before release.
Inside your report
60-page clinical document
Executive summary — 1-page clinician overview
Full gene-by-gene findings with reference ranges
Your variant vs. 100,000-person population norms
Ranked intervention priority list by impact
Supplement & lifestyle protocol tailored to your results
GP & specialist summary letter (formatted for referrals)
Document library access via patient portal 24/7
Report formats included
Digital PDF
Download instantly from your portal
Patient portal
Interactive results, always accessible
GP referral letter
Formatted for your local doctor
Specialist letter
Category-specific clinical summary
Included free with every test
Your patient portal is activated the moment your saliva kit is dispatched. Every result, action item, specialist message, and document — in one place, accessible 24/7 from any device.
Full report library
PDF + interactive results, always accessible
Secure specialist messaging
Direct line to your doctor, included free
Protocol reminders
Daily supplement and action item tracker
Access from any device
Web portal — no app download required
GDPR encrypted storage
Your data is private and deletable on request
Mobile-optimised
Full functionality on phone, tablet, desktop
Your action plan
2/5 done40% complete — tap any item to mark done
Annual ANA/anti-CCP blood test — add to health calendar
Curcumin 1g + piperine daily (IL-6 protocol)
Rheumatology letter generated (HLA-B27)
Dermatology referral letter (FLG null) — download
Vitamin D3 5000 IU — immune optimisation dose
Portal activated instantly on kit dispatch. No app required — web-based access only.
From order to results:
4 simple steps
Everything managed through your patient portal — no clinic visits, no waiting rooms.
Saliva kit sent
Delivered to your door
Lab analysis
ISO 15189 certified lab
Specialist review
Doctor reads your results
Patient portal
Manage everything online
Patient portal: Order your kit, track shipping, view results, message your specialist, and access your complete report — all from one secure dashboard, available on any device 24/7.
Real questions from real patients
These are actual questions asked by patients about their Immune & Autoimmune results — answered in full by our specialists.
Dr. Aylin Kaya
MD PhDMolecular Genetics & Epigenetics Lead
Available for consultations Mon–Fri 9am–5pm (CET)
Dr. Mehmet Yilmaz
MDClinical Genetics & Pharmacogenomics Specialist
Available for consultations Tue–Sat 8am–4pm (CET)
Have a question about your specific situation? Our specialists reply within 2 hours.
Your questions, answered
Start knowing, not guessing.
Get in touch and your coordinator will send you the complete test guide, exact pricing, and your saliva kit within 2 hours. Free, no obligation.
Complete test guide & sample report emailed immediately
Saliva kit dispatched the same working day
Secure patient portal access on day of kit dispatch
Free 15-min pre-test call to answer all your questions
Results in 12 days — reviewed by a specialist before delivery
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HLA Typing & Immune Compatibility
€350 · 12 days · Immune & Autoimmune
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Start your consultation and a coordinator will guide you through the process — pricing, timeline, and everything you need to know.
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