Bone & Joint Health Genetics
Osteoporosis and joint disease risk from your saliva
Identifies variants in VDR, COL1A1, LRP5 and GDF5 that determine your peak bone density potential and lifetime osteoporosis and osteoarthritis risk — actionable from your 20s and 30s.
Istanbul, Turkey
€260
Results in 10 days
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Postal saliva kit — no clinic visit required
Collect from home, post back in the pre-paid envelope. Results delivered digitally in 10 days.
What your saliva
sample reveals
VDR (vitamin D receptor & bone density)
LRP5 & WNT16 (bone mineral density regulation)
COL1A1 (bone collagen — fracture risk)
GDF5 (joint morphology & osteoarthritis risk)
Rheumatology & nutrition recommendations
Best for: Anyone over 40, postmenopausal women, or active individuals wanting to protect long-term joint and bone health
Explore each panel
Browse every category covered in your Bone & Joint Health Genetics — click a marker to see the action it unlocks.
The genes that determine whether your natural physiology favours power, endurance, or mixed-mode sport.
ACTN3 R577X
ACTN3 (chr11)
ACE I/D
ACE (chr17)
PPARGC1A (VO2 max)
PPARGC1A (chr4)
VEGF (Oxygen delivery)
VEGF (chr6)
Turn data into action
Every finding in your report comes with a concrete next step. Here's what your results can unlock.
Redesign Your Training for Your Genetics
Competitive edgeTriggered by: ACTN3, ACE, or PPARGC1A results
+25%
VO2 max improvement with genotype-matched training
Click to collapse
What this result reveals:
Whether your genetic physiology is optimised for power (XX ACTN3 = no fast-twitch protein), endurance (ACE II = exceptional aerobic), or truly mixed — and the specific training split, intensities, and volume that maximise your particular genetic advantage.
Pure endurance genetics (ACTN3 XX + ACE II): 80% zone 2 / 20% threshold — no pure sprint work needed
Shift sport selection or training emphasis to your genetic strengths — the efficiency gains are typically 15–30%
Use your VO2 max response data to set training zones — PPARGC1A results predict how steeply you'll respond to threshold work
Athletes who train to their genetic physiology rather than generic programmes achieve significantly greater performance gains for the same training volume — typically 20–30% better VO2 max response within a season.
Prevent Your Structural Weak Points
Career-protectingTriggered by: COL5A1, COL1A1, or MMP3 variants
−50%
ACL re-injury rate with prehabilitation
Click to see the full action protocol →
Match Your Recovery Protocol to Your Biology
Train smarterTriggered by: CRP, ADRB2, IGF-1 recovery profile
35%
faster HRV recovery with matched protocol
Click to see the full action protocol →
Every action protocol above is included in your digital report, reviewed by a specialist.
Who benefits most
Athlete whose progress has plateaued
Training consistently but results are stagnating. Your genetics reveal whether you're built for endurance, power, or mixed-mode sports — and how to train accordingly.
Managing recurring tendon or joint injuries
The same tendons and joints keep failing under load. Collagen gene variants explain your structural weak points — and prehabilitation can address them before they become chronic.
Planning long-term joint and bone health
Protecting knees, hips, and spine from the inside out. Bone density and osteoarthritis genetics give you a 20–30 year horizon to invest in the right interventions now.
60 pages of actionable insight
Not a raw data dump — a structured clinical report written in plain language, reviewed by your specialist before delivery, with every finding mapped to a concrete action.
Bone & Joint Health Genetics — Genetic Report
Sample results · For illustrative purposes
Endurance
Sport type
ACTN3 XX + ACE II
Elevated
ACL risk
COL5A1 TT
Fast
Recovery rate
Low CRP baseline
High
VO2 max potential
ACE II + VEGF
ACTN3 R577X
Performance
ACE I/D
Performance
PPARGC1A
Performance
VEGF
Performance
+ 6 more markers in your full report
Report delivered digitally in 10 days from sample receipt. Reviewed by a specialist before release.
Inside your report
60-page clinical document
Executive summary — 1-page clinician overview
Full gene-by-gene findings with reference ranges
Your variant vs. 100,000-person population norms
Ranked intervention priority list by impact
Supplement & lifestyle protocol tailored to your results
GP & specialist summary letter (formatted for referrals)
Document library access via patient portal 24/7
Report formats included
Digital PDF
Download instantly from your portal
Patient portal
Interactive results, always accessible
GP referral letter
Formatted for your local doctor
Specialist letter
Category-specific clinical summary
Included free with every test
Your patient portal is activated the moment your saliva kit is dispatched. Every result, action item, specialist message, and document — in one place, accessible 24/7 from any device.
Full report library
PDF + interactive results, always accessible
Secure specialist messaging
Direct line to your doctor, included free
Protocol reminders
Daily supplement and action item tracker
Access from any device
Web portal — no app download required
GDPR encrypted storage
Your data is private and deletable on request
Mobile-optimised
Full functionality on phone, tablet, desktop
Your action plan
2/5 done40% complete — tap any item to mark done
Download personalised training split plan (PDF)
Start ACL prehab programme — physio video library
Collagen 15g + vitamin C 30 min pre-training
Set weekly training load limits (COL5A1 protocol)
HRV baseline test — track recovery in portal
Portal activated instantly on kit dispatch. No app required — web-based access only.
From order to results:
4 simple steps
Everything managed through your patient portal — no clinic visits, no waiting rooms.
Saliva kit sent
Delivered to your door
Lab analysis
ISO 15189 certified lab
Specialist review
Doctor reads your results
Patient portal
Manage everything online
Patient portal: Order your kit, track shipping, view results, message your specialist, and access your complete report — all from one secure dashboard, available on any device 24/7.
Real questions from real patients
These are actual questions asked by patients about their Sports & Fitness results — answered in full by our specialists.
Dr. Aylin Kaya
MD PhDMolecular Genetics & Epigenetics Lead
Available for consultations Mon–Fri 9am–5pm (CET)
Dr. Mehmet Yilmaz
MDClinical Genetics & Pharmacogenomics Specialist
Available for consultations Tue–Sat 8am–4pm (CET)
Have a question about your specific situation? Our specialists reply within 2 hours.
Your questions, answered
Start knowing, not guessing.
Get in touch and your coordinator will send you the complete test guide, exact pricing, and your saliva kit within 2 hours. Free, no obligation.
Complete test guide & sample report emailed immediately
Saliva kit dispatched the same working day
Secure patient portal access on day of kit dispatch
Free 15-min pre-test call to answer all your questions
Results in 10 days — reviewed by a specialist before delivery
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Bone & Joint Health Genetics
€260 · 10 days · Sports & Fitness
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Start your consultation and a coordinator will guide you through the process — pricing, timeline, and everything you need to know.
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